Our study documents the shelf, shelf-edge, slope, and basin-floor depositional facies characteristics, stratigraphic variations, and sedimentation trends of the Missourian Canyon Group and Virgilian–Wolfcampian Cisco Group across the southern Eastern Shelf and the adjacent Midland Basin. The Canyon Group (base Palo Pinto Limestone to top Home Creek Limestone) consists of an aggradational carbonate bank succession having locally prominent reef facies. Similar reef facies continued to accumulate during early Cisco sedimentation.